Pregnancy achieved through IVF requires medical supervision and the use of medications to support embryo implantation in early pregnancy development, which differs from natural pregnancy.
1. Hormone Use
IVF Pregnancy:
Progesterone hormone is often administered in the form of injections, vaginal suppositories, or oral medications to prepare the uterine lining for embryo implantation and support the early pregnancy stage.
In some cases, estrogen hormone ( Estradiol) may also be prescribed to help maintain appropriate hormone levels to support the pregnancy.
Natural Pregnancy:
The body naturally produces progesterone hormone without the need for additional hormones supplementation.
2. Miscarriage Prevention
IVF Pregnancy: Pregnancy achieved through IVF may carry a higher risk of early miscarriage. Therefore, additional medications may be prescribed to reduce risks, such as those addressing blood clotting issues that could hinder blood flow to the embryo.
Natural Pregnancy: In natural pregnancy, such medications are typically not required unless specific complications arise.
3. Immune System Adjustment
IVF Pregnancy: In some cases, immunosuppressive medications (such as Prednisolone) may be used to reduce immune responses that could affect embryo implantation.
Natural Pregnancy: In natural pregnancy, the immune response is typically regulated naturally in women without underlying immune disorders.
4. Duration of Medication Use
IVF Pregnancy: Progesterone and estrogen are typically used continuously until the 10th to 12th weeks of pregnancy, or until the placenta can produce sufficient hormones on its own.
Natural Pregnancy: The body naturally adjusts hormone production without the need for supplemental hormones medications.
5. Close Monitoring
IVF Pregnancy: Women undergoing IVF typically require more frequent monitoring of hormone levels and pregnancy development, including early ultrasound examinations.
Natural Pregnancy: Monitoring usually begins around the 8th to 10th weeks of pregnancy, unless there are specific medical indications.
6. Other Medications to Prevent Complications
IVF Pregnancy: Additional medications, such as vitamin D, folic acid, and other supplements, may be prescribed based on individual needs.
Natural Pregnancy: Vitamins or supplements may be recommended as usual, but there is generally no need for special supportive medications.
Pregnancy resulting from IVF is more complex, so it requires more careful management and the appropriate use of medications, making it more systematic than a natural pregnancy. 
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